2021-04-10 · Similarly within-individual and between-individual biological variations were higher for both TSH and FT4 at birth and also declined with age. Our data were broadly similar to previous studies. Significant heterogeneity in study population and methods prohibited direct numerical comparison between this and previously published studies.
The aim of our study was to assess: (i) the average inherent intra‐ and inter‐ individual biological variation (CVi and CVg) for CA 19‐9, CEA, AFP in a group of
Hence, we should expect markers of individual biological age to explain variation in the strength of the stress response that cannot be explained by chronological age alone. Variation | Genetics | Biology | FuseSchoolLook at these baby animals. You will have immediately observed how cute and fluffy they are but you willalso have Besides biological variation, lipid values are also dependent on the laboratory's analytical performance. Today's chemistry analyzers are very precise; analytical variation in reputable laboratories is less than one half of biological variation.
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The intricacies of human biology with its many layers of interconnecting networks and inbuilt redundancy evolved over many millions of years to maximize an individual's chance of survival. Individual Biological Variation. By now the reader will have readily grasped one of the key working principles of clinical ecology which is that of individual biological variation. With such a bewildering array of potential responses to stressors and overload, it is virtually impossible to make generalizations. Individual Biological Test Variation One analytical goal that each laboratory should strive for is to make method imprecision for each analyte equal to or less than one half of the average intra-individual biological variation. As of May 2019, EFLM is managing the new biological variation database.
Individual variation in drug response Prescribers have numerous sources of guidance about how to use drugs appropriately (e.g. dose, route, frequency, duration) for many conditions. However, this advice is based on average dose–response data derived from observations in many individuals.
1Department of Cardiovascular Sciences, Academic Unit of Emergency Medicine, University of Leicester, Leicester, UK In the biological sciences, the quantity being measured is seldom unchanging and stable, and the variation observed might additionally be intrinsic to the phenomenon: It may be due to inter-individual variability, that is, distinct members of a population differing from each other. DOI: 10.1016/J.CLINBIOCHEM.2011.03.123 Corpus ID: 58498035.
1 Mar 2018 population-based reference ranges, assessing variation in serial results from an individual, and determining the optimal sample for analyzing a
Carobene A. BACKGROUND: Biological variation (BV) data enable assessment of the significance of changes in serial measurements observed within a subject and are used to set analytical quality specifications. Biological variation has generally been defined as random fluctuation around the homeostatic set point for each individual (within-subject or intra-individual biological variation) and the 2015-03-19 Chance differences in the true and recorded values may result in an apparent association between an exposure and an outcome, and such variations may arise from unbiased measurement errors (e.g. weight of an individual can vary between measurements due to limited precision of scales) or biological variation within an individual (e.g.
33, 2015 Human cooperation in groups: variation begets variation. Summary. By ratifying the Convention of Biological Diversity, Sweden has agreed to ting leads to increased migration of individuals (and genes) from nearby. 1. between-subject biological variability. (substantiv), variabilidad biológica interindividual (substantiv, femininum).
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Identification of phenotype and genotype, dominant and recessive Individual Variation. IN THE The variation seen between the individuals of any population biology or even of genetics per se, but of nuclear biochemistry. Measuring differences between individuals in a population (population of beans).
Clin Chem 1987;33:670–3. Single analyst and analytical system. Single or very small number of batches. Preferred Protocol: Cotlove et al.
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Most features of an individual phenotype are polygenic and show continuous variation. Identification of phenotype and genotype, dominant and recessive
These are often central to monitoring health and informed decision making. Major causes of variation include mutations, gene flow, and sexual reproduction.
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Biological mechanisms and individual variation in fibrinolysis after major trauma Timothy J Coats , 1 Mohamed Morsy1,2 To cite: Coats TJ, Morsy M. Emerg Med J maintain a balance. A lack of balance can lead to 2020;37:135–140. 1Department of Cardiovascular Sciences, Academic Unit of Emergency Medicine, University of Leicester, Leicester, UK
DOI: 10.1016/J.CLINBIOCHEM.2011.03.123 Corpus ID: 58498035.